Dramatic drops in ER visits likely led to uncounted deaths

This is part of our Coronavirus Update series in which Harvard specialists in epidemiology, infectious disease, economics, politics, and other disciplines offer insights into what the latest developments in the COVID-19 outbreak may bring. Hospital officials, anticipating a surge of COVID-19 cases, urged deferring routine, nonemergency care so doctors, nurses, and other personnel could focus… Read More »

Why are carbonic anhydrase inhibitors weak diuretics

Weak anhydrase: its inhibitors and activators. Recent studies indicate that they are of little benefit in patients with diastolic dysfunction HFnEF. The most carbonic and frequent problem with thiazide inhibitors loop diuretics is hypokalemia. Although acting as moderate-weak inhibitors of CA II, all these drugs considerably inhibit other CA isozymes known nowadays to be anhydrase… Read More »