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Description 1. What is Percocet Percocet contains a combination of acetaminophen and oxycodone. Oxycodone is in a group of drugs called opioid pain relievers. An opioid is sometimes called a narcotic. Acetaminophen is a less potent pain reliever that increases the effects of oxycodone. Percocet is used to relieve moderate to severe pain.Percocet may also… Read More »