If your institution subscribes to this resource, and you don’t have a MyAccess Profile, please contact your library’s reference desk for information on how to gain access to this resource from off-campus. Appreciate the importance of cholesterol as an essential structural component of cell membranes and as a precursor of all other steroids in the body, and indicate its pathological role in cholesterol gallstone disease and atherosclerosis development. Understand the role of 3-hydroxymethylglutaryl CoA reductase HMG-CoA reductase in controlling the rate of cholesterol synthesis and explain the mechanisms by which its activity is regulated. Appreciate that cholesterol balance in cells is tightly regulated and indicate the factors involved in maintaining the correct balance. Explain the role of plasma lipoproteins, including chylomicrons, very low density lipoprotein VLDL, low-density lipoprotein LDL, and high-density lipoprotein HDL, in the transport of cholesterol between tissues in the plasma. Appreciate the importance of bile acid synthesis not only in the digestion and absorption of fats but also as a major excretory route for cholesterol.
No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. The excretion and reabsorption of bile acids forms the basis of the enterohepatic circulation, which is essential for the digestion and absorption of dietary fats. Upon binding of apolipoprotein B, many LDL receptors become localized in clathrin-coated pits. These are the five main types. When mice are fed a high lipid diet, fecal neutral sterol excretion is increased[ 20 – 22 ].
Apologise but how cholesterol excreted from body think that you
Cholesterol has a bad reputation, thanks to its well-known role in promoting heart disease. Excess cholesterol in the bloodstream is a key contributor to artery-clogging plaque, which can accumulate and set the stage for a heart attack. However, the role of cholesterol in your body is not all negative. To fully explain cholesterol, you need to realize that it’s also vital to your health and well-being. Although we measure cholesterol production in the blood, it’s found in every cell in the body. The Harvard Special Health Report Managing Your Cholesterol explains cholesterol as a waxy, whitish-yellow fat and a crucial building block in cell membranes.